![]() Otherwise, angiokeratomas are generally harmless lesions that do not mandate intervention. As this condition benefits from early intervention, a high suspicion should be maintained when widespread angiokeratomas are found, with early subsequent specialist referral. 5 Answer 6Īs described, angiokeratoma corporis diffusum is a serious genetic condition with the potential for multiple-organ involvement because of the widespread inappropriate glycolipid deposition. 5 The vascular lesions associated with this condition occur on the trunk and proximal limbs and manifest before puberty. 5 There is a subsequent broad scope of potential complications, including renal failure, cardiomyopathy, gastrointestinal distress and neuropathy. This manifests in the context of Fabry disease, a rare, serious, recessive X-linked condition that results in a deficiency of lysosomal enzyme alpha-galactosidase A, which leads to an accumulation of glycolipid in many tissues, including skin, heart and kidneys. The systemic form is angiokeratoma corporis diffusum.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |